Tapentadol 200 mg – Shipped from USA
Key Information
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- Mechanism of Action: Tapentadol 200 mg tablet works in two ways: it acts as a mu-opioid receptor agonist and also inhibits the reuptake of norepinephrine in the brain and spinal cord, which helps to block pain signals. This dual mechanism makes it effective for both standard pain and neuropathic pain.
- Indications: It is prescribed when other pain treatments have not been effective or cannot be tolerated. Extended-release formulations of the 100 mg dose are specifically indicated for daily, around-the-clock management of severe chronic pain, including pain related to diabetic neuropathy. The immediate-release version is used for acute pain.
- Dosage: The typical dose for an immediate-release tablet is 50 mg to 100 mg every 4 to 6 hours, with a maximum of 600 mg in 24 hours. For the extended-release form, a common starting dose is 50 mg twice daily, which can be increased to between 100 mg to 250 mg orally twice a day.
- Side Effects: Common side effects include extreme drowsiness, confusion, difficulty breathing, and fainting. Serious potential side effects include respiratory depression, seizures, and serotonin syndrome.
- Precautions:
- It should not be taken with alcohol or other medications that cause drowsiness.
- It should be used with caution in patients with a history of seizures, head injuries, liver or kidney disease, or breathing problems.
- Do not use with monoamine oxidase inhibitors (MAOIs).
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